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Benefits:
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• PROMOTES THE ERECTILE FUNCTION OF THE PENIS WITH FIRMER AND HARDER ERECTIONS • INTENSIFIES YOUR LIBIDO AND APPETITE FOR SEXUAL PLEASURE • STRENGTHENS YOUR SEXUAL STAMINA
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How VigaPlus™ works?
VigaPlus™ works on the same principle as VIAGRA, CIALIS and LEVITRA
It works by increasing the Nitric Oxide level in the blood plasma, which causes the smooth muscles to relax leading to vasodilation of the penile arteries and thereby an erection.
Scientific explanation:
NO is produced from the amino acid L-arginine by the enzymatic action of nitric oxide synthase (NOS). There are two endothelial forms of NOS: constitutive NOS (cNOS; type III) and inducible NOS (iNOS; type II). Under normal, basal conditions in blood vessels, NO are continually being produced by cNOS. When NO forms, it has a half-life of only a few seconds, in large part because superoxide anion has a high affinity for NO (both molecules have an unpaired electron making them highly reactive). Therefore, superoxide anion reduces NO bioavailability. NO also avidly binds to the heme moiety of haemoglobin (in red blood cells) and the heme moiety of the enzyme guanylyl cyclase, which is found in vascular smooth muscle cells and most other cells of the body. Therefore, when NO is formed by vascular endothelium, it rapidly diffuses into the blood where it binds to haemoglobin and subsequently broken down. It also diffuses into the vascular smooth muscle cells adjacent to the endothelium where it binds to and activates guanylyl cyclase. This enzyme catalyzes the dephosphorylation of GTP to cGMP, which serves as a second messenger for many important cellular functions, particularly for signalling smooth muscle relaxation.
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